Hormonal shifts during perimenopause can leave many women feeling off—physically, mentally, and emotionally. From brain fog and fatigue to weight gain and irregular cycles, these changes are more than inconvenient—they're signs that your body needs targeted support.
One often-overlooked mineral that plays a powerful role in this transition is iodine. Essential for thyroid health, metabolism, and hormone regulation, iodine may be the missing piece for women navigating perimenopause and menopause. Finding a natural iodine supplement that easily fits your routine doesn't have to be complex, but first, here's the why.
Why Iodine Matters in Perimenopause

Your thyroid regulates metabolism, energy, mood, and hormonal balance—and it relies on iodine to function. As estrogen and progesterone fluctuate, so does thyroid function. Many women in perimenopause begin to experience mild iodine deficiency, especially if they’ve cut back on iodized salt or follow plant-based diets.
The World Health Organization estimates that more than 2 billion people globally are iodine deficient, with women of reproductive age among the most affected groups.
5 Natural Ways to Support Hormonal Balance with Iodine
1. Fuel Your Thyroid Function
The thyroid produces hormones (T3 and T4) that regulate your heart rate, body temperature, metabolism, and cognitive performance. Iodine is a structural component of both hormones—without it, the thyroid simply can’t function. During perimenopause, fluctuating estrogen levels can place additional stress on the thyroid, leading to symptoms like fatigue, cold sensitivity, irregular cycles, and slowed metabolism.
A mild iodine deficiency can snowball into greater hormonal disruption if left unaddressed. Adding iodine through a bioavailable, ocean-sourced supplement like Crane Wellness' Pure Oceanic Root Iodine gives your thyroid the raw material it needs to stay active and balanced. This supplement contains 300 mcg of iodine per serving, meeting 200% of the Daily Value, which is considered safe and effective for addressing deficiency in most adults.
Pairing iodine with selenium, zinc, and B vitamins can further support thyroid hormone conversion and utilization.
2. Balance Mood and Mental Clarity

Hormonal changes during perimenopause can affect neurotransmitter activity in the brain, leading to irritability, anxiety, forgetfulness, or mood swings. This is not "just aging"—it’s a biochemical shift. Iodine influences brain function indirectly through thyroid hormones, which play a key role in regulating serotonin and dopamine levels.
Inadequate thyroid activity due to low iodine can leave you feeling mentally foggy or emotionally unstable. One study in Biological Trace Element Research found that women with sufficient iodine intake reported improved mood and cognitive resilience during hormonal transitions.
Crane’s formula includes magnesium, which helps regulate the nervous system and supports sleep, focus, and emotional steadiness. Other supportive nutrients include omega-3 fatty acids, L-theanine, and adaptogens like ashwagandha or rhodiola.
3. Promote Healthy Metabolism and Weight Management

Weight gain, especially around the midsection, is one of the most common frustrations during perimenopause. Reduced estrogen and thyroid hormone levels can lower resting metabolic rate, slow digestion, and alter fat distribution.
Iodine supplementation can help rev up your thyroid's ability to burn calories, convert food into energy, and regulate temperature and metabolism. Studies have shown that correcting even mild iodine deficiency improves basal metabolic rate and supports lean body mass over time.
Pure Oceanic Root Iodine also contains magnesium, which supports insulin sensitivity and carbohydrate metabolism. For additional metabolic support, consider increasing intake of chromium, fiber-rich foods, and anti-inflammatory spices like turmeric and ginger.
4. Strengthen Immune and Detox Function

During perimenopause, immune resilience often dips, and inflammatory markers tend to rise. Iodine plays a dual role here—supporting immune function and acting as an antioxidant that protects tissues from oxidative stress.
Iodine also assists in detoxifying halogens like bromide and fluoride, which can displace iodine in the body and interfere with thyroid hormone production. When your detox pathways are sluggish, hormone-disrupting chemicals can build up and make symptoms worse.
Crane’s formula includes fucoidan, a seaweed-derived polysaccharide with well-documented anti-inflammatory, antiviral, and immune-supporting effects. Other ingredients that help include milk thistle, chlorella, and cruciferous vegetables like broccoli and kale, which support estrogen metabolism and liver detox.
5. Maintain Healthy Skin and Hair

Estrogen helps maintain skin elasticity, hydration, and hair strength. As levels drop during perimenopause, many women notice dry, dull skin, thinning hair, or brittle nails. The thyroid also plays a major role in these processes.
Iodine deficiency can impair skin regeneration and slow the rate of hair follicle activity. A study published in Dermato-Endocrinology linked poor thyroid function to increased skin dryness, poor wound healing, and changes in hair texture.
Restoring iodine and supporting the thyroid can help promote healthier, more youthful skin and hair from the inside out. Pairing iodine with marine collagen, vitamin C, biotin, and hyaluronic acid (like in Crane’s Radiant Renew) can further enhance these visible beauty benefits.
Final Thoughts
Perimenopause doesn’t have to mean feeling out of sync. With the right nutritional support—like clean, ocean-sourced iodine—you can nourish your thyroid, stabilize your hormones, and feel like yourself again.
Crane Wellness’ Pure Oceanic Root Iodine is designed specifically to support women through midlife transitions with the power of nature and the backing of science. Remember, it’s not just about one ingredient—it’s about a holistic approach. Prioritize sleep, manage stress, move your body daily, and nourish your hormones with nutrient-dense foods.
When you give your body what it needs, it knows how to return to balance.