LIMITED TIME HOLIDAY OFFER 2 FREE Travel Size Nattokinase w/ 3 Pack 5 FREE Travel Size Nattokinase w/ 5 Pack FREE SHIPPING + FREE GIFT W/ SUBSCRIPTIONS OVER 1M SOLD
LIMITED TIME HOLIDAY OFFER 2 FREE Travel Size Nattokinase w/ 3 Pack 5 FREE Travel Size Nattokinase w/ 5 Pack FREE SHIPPING + FREE GIFT W/ SUBSCRIPTIONS OVER 1M SOLD

Feel the Flow with Japanese Nattokinase for Heart, Circulation & Longevity

"This is the best Nattokinase I've found" - Jerry, 56, AZ and over 1M people agree

Trusted by Tradition. Backed by Science.

Real People with Real Results

Join over 1 million satisfied customers

"I'm so happy I tried this out. Its been about a month and a half and my blood pressure and my cholesterol numbers are already improving."

James R.

Verified Buyer

"Order arrived quickly and when I had a question about it, I got answers right away. I love that its made in Japan and its a high quality natto"

David D.

Verified Buyer

"This has helped me so much! My circulation in my legs is a lot better, no more cramping. My doctor is shocked all I did was start taking this."

Mary P.

Verified Buyer

Carbon Neutral Shipping
Carbon Neutral Shipping
Made in Japan Since 1974
Made in Japan Since 1974
Science Backed Formula
Science Backed Formula
Tested for Purity & Potency
Tested for Purity & Potency
Sustainably Sourced
Sustainably Sourced
30 Day Guarantee
30 Day Guarantee
GMP, JAS & ISO9001 Certified
GMP, JAS & ISO9001 Certified
Proven to Support Heart Health
Proven to Support Heart Health

Boost Your Circulation, Limited Stock Available

What is Nattokinase?

Nattokinase is an enzyme extracted from Natto, created through the fermentation of soybeans by the beneficial bacteria Bacillus subtilis.

Originating in Japan over 2,000 years ago, Natto has been a staple in traditional Japanese diets, widely regarded as a superfood for promoting longevity and heart health due to its unique enzyme profile.

It recently has become popular for its ability to break down fibrin (that causes clots), regulate blood pressure, improve circulation, and even reduce carotid artery thickness (CCA-IMT) and carotid plaque size, with the right dosages. It has also been shown to benefit lung, liver and brain health.

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Heart Health Benefits of Nattokinase

Cardiovascular Support:

  • Promotes healthy blood flow and circulation.
  • Helps maintain optimal blood pressure levels.

Blood Clot Prevention:

  • Exhibits natural blood-thinning properties, aiding in the prevention of clots.
  • Supports cardiovascular health by enhancing circulation.

Supports Healthy Cholesterol Levels:

  • May aid in reducing unhealthy cholesterol, contributing to overall cardiovascular wellness.

Anti-inflammatory and Antioxidant Benefits:

  • Helps reduce inflammation throughout the body.
  • Provides antioxidant protection, reducing oxidative stress.

Respiratory Health:

  • Supports respiratory health by improving circulation and reducing inflammation in lung tissues.
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Questions About Natto?

  • To maximize health benefits, take Nattokinase regularly:

    Typical dosage: 100 mg or 2,000 FU (Fibrinolytic Units) daily for preventative care.

    Most studies show that at least 4,000 FU per day should be taken to see improvements on heart, artery, blood pressure, endometriosis and more.

    Recent research shows that at least 6,000 FU per day was effective in lowering the level of total cholesterol, triglycerides and low-density lipoprotein cholesterol, and effective in reducing the thickness of the median of the common carotid artery (CCA-IMT) and plaque.

    Some, with conditions related to heart disease need 10,800 FU per day or more. Read this article here for more info on that.

    The answer for this greatly depends on the overall health and age of the individual consuming the supplement.

  • Best consumed on an empty stomach for optimal absorption.

    Best time is generally at night, when your circulation naturally slows down.

    Consistency is key. Incorporate into your daily wellness routine.

  • As with most supplements, results vary based on your current health status. We recommend taking daily for at least 90 days to get the full benefits activated in your system.

    Those with high BMI or high BP or other active circulation issues generally report improvements from 2-5 weeks.

    Those in better health can feel improvements in 4-8 weeks.

    Preventative improvements are hard to measure until longtime and consistent use (6mos-1year or longer)

  • As always, please consult your doctor before starting a new supplement.

    Nattokinase is a natural blood thinner and can lead to bruising or increased bleeding for those on blood thinner medications.

  • Pregnant and breastfeeding women, as well as children and adolescents, should avoid nattokinase due to a lack of sufficient safety data.

  • We believe that setting a routine and consistent use of our products will lead to long-lasting results.

    By signing up for a subscription, you’ll easily be able to build Nattokinase into your routine and receive all the benefits exclusive to our subscribers which include: at least 15% off, free shipping, flexible cancellation, and much more!

    We recommend using Nattokinase Blend daily for at least 90 days for optimal results.

  • Our US office is located in Santa Ana, CA. We are open and ship out all orders by next business day, Monday-Friday. Please keep in mind we are closed on major holidays so our team can be with their families.

    If you need help with your order please chat live, call, or email us and we will be happy to help you right away.

    (888) 388-8785

    info@cranewellness.co

  • The traditional Japanese natto dish does have a potent fermented taste that not all may enjoy. Aside from taste and availability in your local area, the average amount of the nattokinase enzyme is roughly 2,000 FU.

    Our Nattokinase Blend ensures that you can easily consume 6,000FU per day without worrying about cooking or buying nattokinase - or worrying if you will like the taste. It is a more consistent way to enjoy the benefits of nattokinase.

    Plus, our blend includes Aomori Garlic Extract, Okinawa Moromi Vinegar, and GABA to increase potency and boost more health benefits than natto alone.

  • All of our products are made in a GMP, JAS, and ISO9001 facility in Osaka, Japan.

  • Crane Wellness is a US branch of Fine Japan which is based in Osaka, Japan.

    Fine was founded in 1974 by Yoshimasa Sasaki and it is still family owned and operated by his three sons.

    The Crane Wellness branch was established to share our traditional Japanese wellness and beauty supplements with people in the United States and all over the world.

    You can read more about our story on our About Page.

Shop & See Full Details of Nattokinase Blend
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crane wellness nattokinase blend in japanese garden - natural heart health and circulation support

Unique Formula from Japan

Developed with over 50 years of Research

A powerful blend of traditional Japanese ingredients, backed by modern science and made with the highest quality standards.

Nattokinase

Supports cardiovascular health, improves blood circulation and overall longevity

Aomori Garlic Extract

Powerful anti-inflammatory properties and helps boost circulation

Okinawa Moromi Vinegar

Rich in antioxidants for overall wellness, promotes heart health

GABA

Supports healthy circulation and brain health

Plant Based
Plant Based
Non-GMO
Non-GMO
Gluten Free
Gluten Free
Sugar Free
Sugar Free

Scientific Research & Clinical Studies

Nattokinase’s benefits are extensively supported by science and clinical studies:

A 2017 clinical trial published in Scientific Reports demonstrated that daily supplementation with Nattokinase significantly improved circulation and reduced risks associated with blood clots.

A 2017 clinical trial published in Scientific Reports demonstrated that daily supplementation with Nattokinase significantly improved circulation and reduced risks associated with blood clots.

Research from the International Journal of Molecular Sciences (2021) highlights Nattokinase’s potent fibrinolytic (clot-dissolving) capabilities, supporting its use in promoting cardiovascular health.

Research from the International Journal of Molecular Sciences (2021) highlights Nattokinase’s potent fibrinolytic (clot-dissolving) capabilities, supporting its use in promoting cardiovascular health.

Additional studies in the Journal of Nutrition and Food Sciences have underscored its beneficial effects on cholesterol management and overall cardiovascular wellness.

Additional studies in the Journal of Nutrition and Food Sciences have underscored its beneficial effects on cholesterol management and overall cardiovascular wellness.

japanese science and research for crane wellness.jpg__PID:d8b41c9c-c663-4bfb-80e2-5f7a529ccd72
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Why Choose Nattokinase Blend by Crane Wellness?

Unique Japanese Formula

Unique Japanese Formula

6,000 FU Plus Aomori Garlic Extract, Okinawa Moromi Vinegar and GABA for added potency

Premium Ingredients, Tested

Premium Ingredients, Tested

Non-GMO, sustainably sourced, and purity tested.

ISO9001, GMP, and JAS Organic Certified

ISO9001, GMP, and JAS Organic Certified

Produced through advanced fermentation techniques, maintaining the highest quality standards since 1974.

50 Years of Award Winning Research

50 Years of Award Winning Research

Check out the full list of research institutions, health organizations and associations we are active menbers of on our about page.

Learn More About Nattokinase

Discover benefits, insights and tips from experts

The Women’s Guide to Nattokinase: Benefits Beyond Circulation
The Women’s Guide to Nattokinase: Benefits Beyond Circulation
Nattokinase is best known for supporting blood flow—but for women, this Japanese enzyme may also hold promise for hor...
Read More
Nattokinase Myths vs. Facts: Clearing Up Common Misconceptions
Nattokinase Myths vs. Facts: Clearing Up Common Misconceptions
Separate fact from fiction with our guide to nattokinase myths and truths. Learn how this natural enzyme supports hea...
Read More
5 Reasons Why Health Experts Are Turning to Natto for Cardiovascular Health  For centuries, natto—a tradition
5 Reasons Why Health Experts Are Turning to Natto for Cardiovascular Health For centuries, natto—a tradition
Discover the science behind nattokinase—an enzyme from Japanese natto that supports healthy circulation, blood pressu...
Read More
4.8
Rated 4.8 out of 5 stars
Based on 72 reviews
Total 5 star reviews: 57 Total 4 star reviews: 13 Total 3 star reviews: 2 Total 2 star reviews: 0 Total 1 star reviews: 0
97%would recommend this product
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72 reviews
  • Joe T.
    Verified Buyer
    Rated 5 out of 5 stars
    1 week ago
    5 Stars

    Having learned about its cardiovascular benefits that have been enjoyed by wiser folks than I for centuries, it is now a part of my daily supplement regimen.

  • Manuel B.
    Verified Buyer
    Rated 5 out of 5 stars
    1 week ago
    5 Stars

    I can only say is amazing, I felt the difference in my blood pressure and just feel good

  • Shelly H.
    Verified Buyer
    Rated 5 out of 5 stars
    1 week ago
    5 Stars

    Love it. Literally feel that it's helped save my life. Great for the great and blood!!

  • Mark W.
    Verified Buyer
    Rated 5 out of 5 stars
    2 weeks ago
    5 Stars

    Both my wife and I have been taking this supplement for about a month and a half. Lab results for both of us show that our cholesterol levels are down substantially. My wife who is a registered nurse is ecstatic.

  • Glen B.
    Verified Buyer
    Rated 5 out of 5 stars
    2 weeks ago
    Lower blood pressure

    Went to doctor today after 1 month of nattokinase n bp was 125 over 75. Im 64 years old. Wow

  • Kim G.
    Verified Buyer
    Rated 5 out of 5 stars
    1 month ago
    5 Stars

    My blood pressure is down. It’s wonderful!!

  • Michael
    Rated 5 out of 5 stars
    2 months ago
    5 Stars

    So far so good. I was looking for heart support. I believe this is the best natto I could find after an extensive search of the available products

  • Nikki M.
    Verified Buyer
    Rated 5 out of 5 stars
    2 months ago
    5 Stars

    Ive started and love them! Customer service is excellent and resolved my issue seamlessly.

  • Nancy J.
    Verified Buyer
    Rated 5 out of 5 stars
    2 months ago
    5 Stars

    I love this product. I have too many RBCs in my blood so worry about clotting. This nattokinase product has clean ingredients and seems to be the best out there.

  • Anne P.
    Verified Buyer
    Rated 5 out of 5 stars
    3 months ago
    5 Stars

    My circulation is not the best and this genuinely helps in a gentle way- I really like it. Great product! :)

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50 Years of Research

Since 1974, we've won many awards for our science research and product development.

Carbon Neutral Shipping

Sustainability is key. We work with Planet to offset our carbon footprint for carbon neautral shipping on every order.

Regenerative and Sustainable

We source non-gmo only ingredients from regenerative farms, local and sustainable sources as much as possible.